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抗恶性高钙血症药物——唑来膦酸 被引量:2

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摘要 恶性高钙血症(肿瘤引起的高钙血症,TIH)是肿瘤患者中最常见的、危及生命的代谢性疾病[1].它主要是由骨中钙丢失增加而引起的.肿瘤引起体液及旁分泌因子分泌增加,使破骨细胞活性增加和增殖,抑制成骨细胞的活性和增殖,结果导致骨钙再吸收增加而引起血清钙水平的迅速升高[1].
出处 《中国药学杂志》 CAS CSCD 北大核心 2005年第14期1117-1118,共2页 Chinese Pharmaceutical Journal
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参考文献4

  • 1Cheer SM, Noble S. Zoledronic acid [J]. Drugs,2001, 61 (6):799. 被引量:1
  • 2Viereck V, Emons G, Lauck V, et al. Bisphosphonate pamidronate and zoledronic acid stimulate osteoprotegerin production by primary human osteoblasts [ J ] . Biochemical and biophysical research communications ,2002,291(3): 680. 被引量:1
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同被引文献14

  • 1刘瑶,刘治军,傅得兴.新一代二膦酸盐类药物唑来膦酸的药理及临床[J].中国新药杂志,2004,13(11):1058-1060. 被引量:11
  • 2Evdokiou A, Labrinidis A. Induction of cell death of human osteogenic sarcoma cells by zoledronic acid resembles anoikis[J]. Bone, 2003, 33(2):216-228. 被引量:1
  • 3Reid IR, Gamble GD, Mesenbrink P, et al. Characterization of and risk factors for the acute-phase response after zoledronic acid[J]. J Clin Endocrinol Metab, 2010, 95(9):4380-4387. 被引量:1
  • 4Dicuonzo G, Vincenzi B, Santini D, et al. Fever after zoledronic acid administration is due to increase in TNF-alpha and IL- 6[J]. J Interferon Cytokine Res, 2003, 23(11):649-654. 被引量:1
  • 5Alegre A,Gironella M,Bailén A,et al.Zoledronic acid in the management of bone disease as a consequence of multiple myeloma:a review[J].Eur J Haematol,2014,92(3):181-188. 被引量:1
  • 6Reid IR,Gamble GD,Mesenbrink P,et al.Characterization of and risk factors for the acute-phase response after zoledronic acid[J].J Clin Endocrinol M etab,2010,95(9):4380-4387. 被引量:1
  • 7Lowe NM,Mitra SR,Foster PC,et al.Vitamin D status and markers of bone turnover in Caucasian and South Asian postmenopausal women living in the UK[J].Br J Nutr,2010,103(12):1706-1710. 被引量:1
  • 8Evdokiou A,Labrinidis A.Induction of cell death of human osteogenic sarcoma cells by zoledronic acid resembles anoikis[J].Bone,2003,33(2):216-228. 被引量:1
  • 9Dicuonzo G,Vincenzi B,Santini D,et al.Fever after zoledronic acid administration is due to increase in TNF-alpha and IL-6[J].J Interferon Cytokine Res,2003,23(11):649-654. 被引量:1
  • 10Lewiecki EM.Intravenous zoledronic acid for the treatment of osteoporosis:the evidence of its therapeutic effect[J].Core Evid,2010,4(4):13-23. 被引量:1

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