摘要
目的:探讨呼吸系统疾病患者院内肺部真菌感染的易患因素,临床特征和治疗。方法:应用回顾性调查方法对86例院内肺部真菌感染的有呼吸系统基础疾病的患者进行分析。结果:在呼吸系统疾病患者中,院内肺部真菌感染发生率为1.7%,COPD是继发院内肺部真菌感染最常见的基础疾病,长期使用广谱抗生素,长期使用激素、低蛋白血症、机械通气、合并糖尿病是主要诱因。肺部真菌感染的临床表现无特异性,确诊需结合痰培养和临床情况来定,病原菌以白色念珠菌为主,氟康唑疗效好。结论:院内肺部真菌感染是呼吸系统疾病继发感染的重要原因,常因二重感染导致患者预后极差,应引起临床高度重视。
Ohjective ：To study the suseeptible factors,clinical feature and treatment of nosocomial pulmonary fungal infection in respiratory patients. Methods ：The clinical files of 86 patients with nosocomial pulmonary fungal infection admitted from Jan 2001 to Jun 2004 in Department of Pulmonary Medicine, the First Affiliated Hospital of Chongqing Medical University were reviewed. Results： incidence of nosocomial pulmonary fungal infection was 1.7 %. ODPD was the main predisposing disease, and Candidiasis was the most.The frequent susceptible factors associated with nosocomial pulmonary fungal infection included long- term use of broad - spectrum antibiotics, long- term use of adrenocortical steroid, hypoalbuminemia, mechanical ventilation, and diabetes mellitus. Clinical feature was non - specific. Fluconazole had better clinical effects on treatment. （5）nclusion ： Nosocomial pulmonary fungal infection is an important cause of the secondary infection in respiratory disease. The clinical feature is non - specific. Clinicians should pay close attention to it.
出处
《重庆医科大学学报》
CAS
CSCD
2005年第4期607-609,共3页
Journal of Chongqing Medical University
关键词
肺
院内感染
真菌
临床分析
Lung
Nosocomial infection
Fungal
Clinical analysis
