摘要
目的研究子宫内膜异位症(EMT)r-AFS分期与腹腔镜术后联合促性腺激素释放激素激动剂(GnRH-a)疗效的相关性。方法76例EMT伴不孕患者经腹腔镜卵巢子宫内膜异位囊肿剔除、烧灼异位灶、粘连分离术治疗,术中行EMT的r-AFS分期,轻度组37例,重度组39例。轻、重度组再分单纯腹腔镜术治疗组和联合GnRH-a治疗组,并行随访1a的临床疗效比较,分析各组的症状缓解、年复发率和妊娠等情况。结果轻度EMT组的单纯腹腔镜术治疗组的症状缓解率、年复发率和妊娠率与联合GnRH-a治疗组差别无显著性。重度EMT组的单纯腹腔镜术治疗组的症状缓解率和年复发率与联合GnRH-a治疗组差别无显著性,但妊娠率差别有显著性。结论重度EMT腹腔镜术后联合GnRH-a可以提高妊娠率。轻度EMT腹腔镜术后是否一定要联合GnRH-a来提高妊娠率,有待进一步研究。
[Objective] To assess the therapy of laparoscopic ovarian cyst enucleation, burn and adhesiotomy plus gonodotropine releasing hormone agonist （GnRH-a） in different subgroups of Endometriosis （EMT）. [Methods] 76 cases with EMT and infertility who accepted laparoscopic surgery （LS） were divided into mild and severe groups according to r-AFS Criteria for EMT, and followed up 1 year. Moreover, two groups were divided into therapeutic subgroup （LS plus GnRH-a） and control subgroup （LS）. Data of remission, recurrence and pregnancy after treatment were collected and analyzed. [Results] There was not significant difference in the ratios of remission, recurrence and pregnancy between control and therapy subgroups in mild EMT group. The same results of remission and recurrence happened to severe EMT group, however, a high ratio of pregnancy was revealed. [Conclusions] LS plus GnRH-a may increase the opportunity of pregnancy in severe EMT. It was a doubt to adopt the therapy of LS plus GnRH-a for pregnancy in mild EMT.
出处
《中国内镜杂志》
CSCD
北大核心
2005年第7期673-675,678,共4页
China Journal of Endoscopy
