摘要
目的:总结胰腺黏液性囊性肿瘤的临床特点,提高对胰腺黏液性囊性肿瘤的认识和诊治水平。方法:对1991至2004年我院收治的43例胰腺黏液性囊腺瘤和囊腺癌的患者临床资料进行回顾性分析。结果:本组43例,男22例、女21例;黏液性囊腺瘤20例,年龄30～71岁,平均年龄(48.6±11.4)岁,病史10d至2年,肿瘤平均大小(9.2±2.4)cm;黏液性囊腺癌23例,年龄37～78岁,平均(52.3±11.9)岁,病史3个月至11年,肿瘤平均大小(14.2±6.3)cm。临床表现主要为病程相对较长的上腹部肿块和疼痛;辅助检查无明显特征性。行根治性切除术32例,囊肿外引流术1例,囊肿空肠吻合术2例,恶性肿瘤姑息性手术6例,未手术2例。术后随访,黏液性囊腺瘤术后无复发及转移,黏液性囊腺癌5年生存率为60%。结论:黏液性囊腺瘤是癌前病变,从黏液性囊腺瘤到囊腺癌是一个逐渐演变过程,进展相对缓慢,临床表现缺乏特异性;术前确诊困难,根治性切除术是最有效的治疗,术后预后较好。
Objective：To summarize the clinical features of pancreatic mucinous cystic tumors and to upgrade their diagnosis and treatment . Methods： A retrospective clinical analysis was conducted in 43 patients with pancreatic mucinous cystic tumors confirmed by operation and pathology,who were treated in our hospital from 1991 to 2004. Results; Of the 43 patients （22 male and 21 female）, 20 had mucinous eystoadenoma （mean age, 48.6 years; mean diameter, 9.2 em） and 23 had mucinous eystoadenoeareinoma （mean age, 52.3 years; mean diameter, 14.2 era）. Fouty one patients underwent surgical treatment with radical operation performed in 32 patients and palliative operation in 6 patients with liver metastasis. The other 3 patients received intra drainage or ex-drainage, No post operative recurrence or metastasis was observed in patients with muninous cystoadenoma, and the 5 year survival rate was 60% in patients with eystoadenoearcinoma. Conclusion： Pancreatic mumnous cystoadenoma is a premalignant lesion which gradually progresses to malignancy. The progression of pancreatic muninous tumors is comparatively slow and the presenting symptoms are usually nonspeeifie. Pre-operative diagnoses and differential diagnoses are usually difficult and radical resection is the most effective treatment with relatively good prognosis.
出处
《第二军医大学学报》
CAS
CSCD
北大核心
2005年第8期856-858,共3页
Academic Journal of Second Military Medical University
基金
国家自然科学基金(30200275).
关键词
胰腺肿瘤
囊隙瘤
囊腺癌
诊断
治疗学
pancreatic neoplasms
cystadenoma
cystoadenoeareinoma
diagnosis
therapeutics
