摘要
本文首次报导了６种由２，６－二氯苯胺得到的席夫碱的合成方法，物理性质，波谱特征和元素分析数据．经生物测试证明，化合物Ｉａ，Ｉｂ和Ｉｆ具有好的植物生长激素方面的活性．
n the 80th have been discovered that some schiff base have good biological activity.Schiff base that substitute aromatic amine react with aromatic aldehydes have good plantgrowth hormones[1.2], Schiff base of cloroaniline and 2,4-(or 3, 4)-dicloroaniline have beenreported[3], We reported there new schiiff base of 2, 6-dicloroaniline in 1993 for the firsttime[']. This paper will reason six new schiff base of 2,6-dichloroaniline are 3-bromobenzal2', 6' -die h ic r op henylaming (la ), 2-c h I o rob enzal, 2 1, 6' --di oh I crop hen yi amin e (fo ), 2methoxybenzal ZI, 6'-dichlorophenylamine (Ic), 2-hydroxybenzal 21, 6'-dichlorophenylamine(Id), 4-hydroxy-3--methoxybenzal 2', 6'--dichlorophenylamine (Ie), benzal acetylene 2', 6'dichlorophenylamine (If).1 Experiment1. 1 Equipments and ReaReutsEquipments: UV-265Ultra violet spectrophotometer, PE￣983 Infrared spectrophotometer, XL-200 MHz Superconducting fi NMR spectrometer, PE--2400 Elemental analyzer.Reagents: p--Aminobenzene sulfonamide: L, Aromatic aldehydes and inorganicreagents: cp1. 2 Syutkesls(1)Synthesis of 2. 6,--dichloroaniline See reference literature[4](2)Synthesis of Compounds la--If[5'6] Equip a 50 mL Circular flask, with water segregator, reflux condenser. Place 0. 02 mol 2,6-dichloroaniline, 0. 021 mol aromatic aldehydes 15mL solvent and tittle catalyst. Heat with oil heating, reflux reacting until water that producein the reaction complete remove. Distillate solvent, distil the residue under reduced pressureor filter off primary product is got. Again distil under reduceed pressure for the liquid products or recrystallise purified for the solid products.2 Result and reasonExperimental results see table l, 2, 3.Table 1 Yield and Dbvsical Drooerties for Combouds la￣fReason@ For large steric effect and attrative--electronic effect, The yield of Schiff base that ismade from 2,6--dichloroaniline are low (usually are 30-40%).@ It is found from the results of biological tests that compounds la and fo have good activiey in property on growth of root, Compoun
出处
《华中师范大学学报（自然科学版）》
CAS
CSCD
1995年第1期55-57,共3页
Journal of Central China Normal University：Natural Sciences
