摘要
颊、舌鳞癌病例７５例，以正常人颊、舌组织为对照，应用ＡＢＣ酶标染色法及透射电镜观察，定量研究了颊、舌癌癌周淋巴管的分布、数量、形态和结构。结果显示：癌原发灶内未见淋巴管，癌周组织中却有丰富的毛细淋巴管分布且明显高于正常颊、舌组织；随着癌的不断浸润、发展，癌周组织中毛细淋巴管数量增多，其密度增高，形态、结构变异，内皮细胞间连接松弛、呈开放状态，同时观察到癌栓经开放之通近侵入毛细淋巴管内。这些结果充分说明了癌周淋巴管增生，增生的淋巴管由于其形态、结构变异，大大增加了疾细胞侵入淋巴道造成转移的机会和可能，这无疑是颈部淋巴结转移率随口腔癌浸润深度增加而上升的重要原因之一。
Abstract The experiment with 75 cases of carcinoma and normal tissues,atudied the distribution,density,morphologic and structural features of the pericarcinoma lymphatics of buccal and lingual spuamous cell carcinoma quantitatively by ABC method and transmission electron microscope.The results showed that there were many lymphaticses and higher in pericarcinoma than in the normal tissues,but no lymphatics were in primary cancer.With growth and development of cancer,lymphatics in the pericarcinoma which density was being high, morphology and structure varied,junction of endothelium was relaxed and opened.Embolus composed by cancer cells could invade into lymphatics through the opened junction.These supposed that lymphatics'proliferation existed in pericarcinoma, and proliferating lymphatics increased chance and probability of cancer cell's invading into lymphatics leading metastasis.This is why tbe ratio of lymphotical nodes metastasis is being high accompanied with invading depth's increasetion of the oral cancer.
出处
《华西口腔医学杂志》
CAS
CSCD
北大核心
1995年第2期130-134,共5页
West China Journal of Stomatology
