摘要
对柱色诸分离的眼镜蛇(N.najaatra)神经毒素脱盐、去锌和镁等,再以小鼠热板法镇痛实验初步证明锌、镁可加强该毒素的镇痛作用。但对Freund佐剂引起的大鼠关节炎,该神经毒素未能显示出消炎作用,且对硫酸锌的消炎作用有所抑制。
The cobra neurotoxin separated by column chromatograph was removedthe salt,Zn and Mg,then,its analgesia experiment was made on mice caused pain by hotplate,The result showed that the Zn and Mg can strengthen the analgesia of the neurotoxin,btit it has no anti-inflammation to rat’s artheritis caused by Freund’s adjuvant,and even caninhibit the anti-inflammation of zinc sulfate.
出处
《湖南中医学院学报》
1995年第3期55-59,共5页
Journal of Hunan College of Traditional Chinese Medicine
基金
省卫生厅资助课题
关键词
蛇毒
眼镜蛇
神经毒
镇痛
消炎
锌
镁
药理学
Cobra neurotoxins/pharmacology
Zn/pharmacology
Mg/pharmacolo-gy
analgesia