摘要
应用经颅多普勒超声技术观察了维脑路通注射液治疗脑外伤动物（兔）模型大脑中动脉血流速度（ＦＶｍｃａ）。此外，用同法又观察了颅脑损伤患者３例。结果发现：使用维脑路通前后兔ＦＶｍｃａ变化明显（Ｐ＜０．０５），表现为用药后兔ＦＶｍｃａ增加；临床应用也取得了同样效果。尤其明显的是用药１～３ｄ后患者即表现出意识、语言和肢体活动的好转。结果提示：维脑路通可改善颅脑损伤后的动物（兔）和患者的颅内血流状态，从而促进脑损伤后神经功能的恢复，但确切机理有待于进一步研究。
The flow velocity in middle cerebral artery(FVmca) of rabbits with head injury was studied by using transcranial Doppler(TCD)after the injection of venoruton. The same way was performed in 3 patients with head injury. The results showed that FVmca had a significant change before and after the administration of injection of venoruton. The same clinical result was obtained. The improvement of consciousness, linguistic function and myodynamia was observed 1～3days after the the injection of venoruton. Venonton might improve the cerebral blood flow in the rabbits and the patients with head injury and , therefore , help the recovery of posttraumatic brain function. However ,further study for exact principle is needed.
出处
《河南医科大学学报》
1995年第3期201-204,共4页
Journal of Henan Medical University
基金
河南省科委资助
关键词
维脑路通
颅脑损伤
药物疗法
动物实验
transcranial Doppler
venoruton
rabbit
human being
head injury
