摘要
本文报告了９７例疟疾患者并发丙型肝炎病毒（ＨＣＶ）感染的原因，发现疟疾患者抗－ＨＣＶ阳性率为７１．１３％，其中有单采血浆还输血细胞（下称单采浆）献血史者为８９．７１％，有受血史者为６４．２９％，既无单采浆史又无受血史者无１例抗－ＨＣＶ阳性。有单采浆史的疟疾患者与同村非疟疾的单采浆献血者相比．抗－ＨＣＶ阳性率无显著不同。在无单采浆史和受血史人群中，疟疾病例和非病例抗－ＨＣＶ阳性率很低．说明有单采浆史的疟疾病例ＨＣＶ感染与单采浆有关，有受血史的疟疾病例ＨＣＶ感染与受血有关。对当地村单采浆血站进行调查，发现在采血、分高血浆和血细胞还输过程中存在血液交叉污染，这是导致有单采浆史的疟疾病例ＨＣＶ感染的主要原因。
The causes of HCV infection among 97 cases of malaria were studied inHebei province. The results indicated that positive rates of anti- HCV were 71. 13% formalaria cases,89. 71 % for that with history of plamapheresis 64. 29 % for that with history ofblood transfusion, and no anti - HCV positive for that without plasmapheresis and bloodtransfusion. The rates had no significant difference between malaria cases with history ofplasmapheresis and plasmapheresis donors at same villages, and it was very low among thecases or noncases without plasmapheresis and blood transfusion, It was showed that HCVinfection of malaria cases was related with plasmapheresis and blood transfusion. Throughinvestigation to operating courses of taking blood. isolating plasma, and return transfusionof blood cells at local plasmapheresis centers, the cross-contamination of blood was found,and it was a main factor to cause HCV infection in cases of malaria.
关键词
疟疾
血清流行病学
丙型肝炎病毒
malaria
HCV antibody
seroepidemiology
plasmapheresis
blood transfusion
