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极低频磁场刺激对心算脑反应的影响 被引量:2

Effect of Extremely Low Frequency Magnetic Field on Brain Response during Mental Arithmetic
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摘要 为探讨极低频磁场(ELMF)对脑功能状态影响的特点,在6名18~20岁健康男性青年中,比较ELMF刺激前后连续和选择心算的行为效果和事件关联电位(ERPs)。结果发现:在第一次刺激后心算正确率显著提高,ERPs中正慢电位(特别是后脑区)亦显著增强;但第二次ELMF剌激后心算正确率和ERPs均出现逆向变化。这表明所用的ELMF刺激可以改善脑功能状态,并可通过ERPs波形变化反映出来,且提示:刺激的效应与脑的基础状态有关。 To study the possible effect of extremely low frequency magnetic field(ELMF)on brainfunction state,behavioral results and event-related potentials(ERPs)during mental arithmetic(MA)were compared in six normal subjects(18~2l yrs) before and after ELMF stimulation. Two types ofMA, succesive and selective addition,were used of which each set was consisted of auditorily inputted30 one-digit numbers.During selective addition only odd or even numbers(Target ) should besummed. There were four sets of test in one experiment with 15 min interval between. ELMF stimula-tions were given after the lst and 3rd sets of test,provided by two parallel coils positioned at each sideof the head which were driven by 5 or 7 Hz triangular signals so that ELMF strengh of 2 and 1 mT atmidpoint was obtained for the lst and 2nd stimulations respectively. Each subject completed two experi-ments on different days with 5 or 7 Hz ELMF stimulation respectively. EEG signals were recordedduring MA at F5,F6,Fz,C5,C6,Cz,P5,P6 nd Pz referenced to the linked mastoids.The results were as follows:The correct rate of both kind MAs were increased after the lst ELMFstimulation,and reached 100%in the 3rd set of test, but declined after the 2nd stimulation. Interest-ingly, the slow positive potentials in the Target-ERPs at posterior brain regions revealed changes par-alleled with the behavioral resuls. Significant correlations(P<0. 025 or P < 0. 01 ) were found be-tween the correct rates and the areas under Target-ERPs from 200 to 400 ms after auditory input forsuccesive and from 200 to 600 ms for selective addition.The results suggest that ELMF stimulationmay improve the brain function state,but the effect is dependent upon the concurrent brain state.
出处 《航天医学与医学工程》 CAS CSCD 1995年第2期99-105,共7页 Space Medicine & Medical Engineering
关键词 磁场 磁效应 脑功能 事件关联电位 magnetic field magnetic effect mental performance brain function event-relatedpotentialsAddress reprint requests to:WEI Jinhe. Institute of Space Medico-Engineering, Beijing 100094,China
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