摘要
对42例习惯性鼾症伴高血压患者进行动态血压监测和晨晚间血浆血管紧张素Ⅰ（AngⅠ）、血管紧张素Ⅱ（Ang Ⅱ）测定。结果显示鼾症组夜间血压较白昼无明显降低,昼夜节律消失。晨间Ang Ⅰ和Ang Ⅱ比晚间增高（P<0.01）。与对照组比较动态血压多项参数和血浆Ang Ⅰ、Ang Ⅱ均有非常显著性差异（P<0.01）。提示鼾症可因低氧血症激活肾素-血管紧张素系统和儿茶酚胺分泌增加等因素引起夜间血压升高,并加重对靶器官损害,使心脑血管并发症增多。
The purpose of this study was to examine the relationship between snoring,24-hour ambulatory blood pressure, early morning and evening plasma Ang Ⅰ,Ang Ⅱ in 42 cases of essential hypertension patients. It was found that blood pressure of the snoring group did not decrease in the nighttime (non-dipper). The morning plasma Ang Ⅰ,Ang Ⅱ concentrations were higher than those in the evening (P<0. 01). The ambulatory blood pressure parameters and plasma Ang Ⅰ, Ang Ⅱ of snoring group were significantly different (P<0. 01) from those of non snoring group.
出处
《高血压杂志》
CSCD
1995年第4期293-295,共3页
Chinese Journal of Hypertension
关键词
鼾症
高血压
血管紧张素
动态血压监测
hypertension
snoring
angiotensin
ambulatory blood pressure monitoring
