摘要
使用赤灵芝的水提取液、乙醇（３０％）提取液进行鼠伤寒沙门氏菌回复、小鼠骨髓多染红细胞微核和雄小鼠精子畸变等三种致突变试验。剂量为１０００μｇ·皿^（－１）和５０００μｇ／皿^（－１）的鼠伤寒沙门氏菌回复试验的结果为阴性。小鼠在服用７５００ｍｇ·ｋｇ^（－１）的水提取液或２５００ｍｇ·ｋｇ^（－１）的醇提取液时，微核试验和精子畸变试验结果均为阴性。
The mutation tests for Ganoderma lucidum were studied. Trese tests included Ames Test, Micronucleus Test and Teratospermo-induced Test. The results of all these three tests were negative and indicated the Ganoderma lucidum hadn't mutagenic effect to mice at the dose of 7500 mg·kg￣(1) for aqua extract and 2500 mg· kg￣(-1) for ethanol extract.
出处
《安徽医科大学学报》
CAS
1995年第4期277-279,共3页
Acta Universitatis Medicinalis Anhui
关键词
赤灵芝
突变
鼠伤寒沙门氏菌
mutation
salmonella typhimurium
mice
Ganoderma
ames test
micronucleus test
treatospermo-induce test
