摘要
本文采用紫外分光光度法对 CTX 溶液的含量及稳定性进行了实验研究。结果表明:该方法简便可行,本品最大吸收峰在234nm(±1nm)处,CTX 溶液在 pH 3.7—8.0之间稳定,有效期为2.1天,与5%葡萄糖液、10%葡萄糖液、5%葡萄糖氯化钠液、林格氏液、0.9%NaCl 液配伍(25℃),在48小时内含量变化不大,可以联合应用。
The contents and stability of the Cefotaxime(CTX)were determined by ultravielet spec-
trophotometry.The results showed th(?)t the maxium wavelength of absorbance is 234 nm
(±1nm);the CTX solutions are stable in pH 3.7～8.0 and its indate is 2.1 days;the contents
of CTX mixed with 5% Glucose Injection,10% Glucose Injection,5% Glucose Injection with
0.9% Soduim Chloride Injection,Ringer Solution for Injection and 0.9% Sodium Chloride
Injection don't change within 48 hours(at 25℃).So CTX can be Combined with the above
five Injections.
