摘要
采用Nitrocefin法和琼脂稀释法对本室近6年从临床分离的322株大肠杆菌的β-内酰胺酶及对氨苄青霉素耐药进行了检测，并就两者的关系进行了初步探讨．结果显示：322株大肠杆菌，78．9％的菌株产β-内酰胺酶，70．2％的菌株对氨苄青霉素耐药；产β-内酰胺酶菌株有84．2％耐氨苄青霉素，而非产β-内酰胺酶菌株仅有17．7％耐氨苄青霉青，经x2检验，P＜0．01．表明临床分离大肠杆菌在产β-内酰胺酶和耐氨苄青霉素方面均较为普通，且产β-内酰胺酶是其对氨苄青霉素耐药的主要途径．
the alactamases and resistance to ampiciIlin were tested in E coli isolated in the latest6 yesrs by Nitrocefin and ager dilution method In 322 isolates of E. coli, β-lactamase- producingstrains accounted for 78. 9%, and 7O. 2% the strains were found resistant to ampicillin. About 82.4% of the alactamase-Preducing strains were resistant to ampicillin, but only l7. 7% of the alacta-mase-negative strains were resistant to ampicillin (Chi-Square test, P<0. 01 ). The results show thatβ-lactamases and resistance to ampicillin both are common in clinical isoIates of E. coli,and that β-lactamases are imPOrtant cause of the deelopment of resistance to ampicillin in E. coli.
出处
《泸州医学院学报》
1995年第4期247-249,共3页
Journal of Luzhou Medical College
