摘要
本文介绍了1990～1993年我院住院的19例老年高尿酸肾病患者.除血尿酸升高外,全部患者伴有不同程度的高血压和肾损害.往往伴有关节痛和肾结石.老年患者常因饮酒过量、高嘌呤饮食、受凉、劳累诱发.以下几点有助于诊断:①本病老年患者并不少见;②肾功能减退进展缓慢,早期以肾小管功能损害为主;③血尿酸升高与肌酐不成比例,血尿酸/血肌酐可>2.5;④痛风肾病有典型临床表现,而原发肾小球疾病即使尿酸很高也很少发生关节炎等改变;⑤肾活检可助鉴别.
19 senile patients were investigated between 1990 to 1993. Besides blood uric acids is high, all patients had diverse degrees of renal impairment and hypertension. In the prime of hyperuricemia nephropathy, it may be complicated by joint pain and nephrolith, It is induced attack by way of alcoholism, hyper pcerine diet, cold, fatigue and so on. The author suggest that the detection of the differentiation of hyperuricemia nephropathy might be useful by the criteria listed as follows: (1)Gout nephropathy is not rare in senile patients. (2)In contrast with the glomerule diseases the renal function decrease of gort nephropathy is slower. Damage influences major the renal tubule funotion. (3)The blood uric acids of gout nephropathy is higher than the creatinine. (4) Glomerule disease absense of characteristic symptoms of gout. They seldom induce arthrutis nephrolith and tophus even when the level of uric acid is very high. (5)Renol biopsy has diagnostic value.
关键词
高尿酸血症
肾损害
诊断
老年人
Hyperuricemia Renal impairment Diagnosis Clinical features
