摘要
对２４０例患者行整夜多导睡眠图监测及睡前、醒后肘部血压测定，呼吸紊乱指数（ＡＨＩ）＞５的１００例为阻塞性睡眠呼吸暂停综合征组（ＯＳＡＳ组），１４０例ＡＨＩ≤５的为对照组，发现ＯＳＡＳ组由睡前血压１７．６±３．０／１１．８±１．９ｋＰａ（１３２．３±２２．５／８８．２±１４．６ｍｍＨｇ）至醒后血压１９．７±３１／１３．１±２．２ｋＰａ（１４７．８±２３．４／９８．６±１６．２ｍｍＨｇ）明显增高（Ｐ＜０．００１），较对照组睡前血压１５．５±１．５／１０．５±１．０ｋＰａ（１１６．２±１１．６／７８．４±７．６ｍｍＨｇ），醒后血压１５．０±１．５／１０．５±１．３ｋＰａ（１１２．４±１１．２／７８．６±１０．０ｍｍＨｇ）明显升高（Ｐ＜０．００１），ＯＳＡＳ组最低血氧饱和度６０．６±１８．２％较对照组８６．２±５．０％明显降低（Ｐ＜０．００１），ＯＳＡＳ组６８％确诊为高血压病，且ＯＳＡＳ经有效治疗后血压也下降接近正常或部分下降，提示ＯＳＡＳ患者夜间反复呼吸暂停引起的低氧血症可能是部分高血压病原因之一。
Abstract Two hundred and forty patients were monitored by polysomnography all through the night. Blood pressures before and after sleep were measured. While 100 patients with AHI>5 as OSAS group, 140 cases AHI≤5as control group. It was found that the blood pressure in OSAS group before sleep was 132.3±2.5/88.2±14. 6mmHg,after sleep was 147. 8±23. 4/98. 6±16.2mmHg (P<0.001) which were much higher than 116.2±11. 6/78. 4±7. 6mm Hs vs 112. 4±1.2/78.6±10.0 mm Hg in the control group(P<0.001).The lowest SaO_2 was 60. 6±18.2% in OSAS group and was 86.2±5. 0% in control group (P<0.01).68% of the patients in OSAS group were diagnosed as essential hypersion. But their blood pressure levels were decreased afterefficient treatment, part of them even to normal level.Thus , hypoxemia may be considered as one of the cause of some patients with hypertension. 1 mmHg=0. 133kpa
出处
《中华心血管病杂志》
CAS
CSCD
北大核心
1995年第5期345-347,共3页
Chinese Journal of Cardiology
