摘要
我院对１０７例原发性肝癌病人肝切除术后血清ＡＦＰ代谢进行了前瞻性研究，测得术后ＡＦＰ的半衰期为３．０～９．５天。资料表明肿瘤大小、转氨酶和术前ＡＦＰ值对ＡＦＰ半衰期无影响。ＡＦＰ半衰期是估测原发性肝癌术后预后的有用指标，当ＡＦＰ半衰期在３．０～９．５天内，意味着肝切除术是根治性的，预后较好；如果ＡＦＰ半衰期超过９．５天，手术可能是姑息性切除，应予积极辅助治疗。
The metabolism of serum alpha fetoprotein(AFP) in l07 patients with
primary livercarcinoma (PLC) was prospectively studied after hepatectomy. The half-life of AFP
in theseries was 3.0～9.5 days. These data showed that the tumour size, serum
alanineaminotransferase (ALT)and preoperative AFP value had no influence on the half-life of
AFP.The half-life of AFP was a useful monitor for the prognosis of patients with PLC
afteroperation. If the half-life of AFP after hepatectomy was within 3.0～9.5 days, it meant
thatthis hepatectomy was a radical resection. If the half-life of AFP after hepatectomy was
longerthan 9.5 days, this hepatectomy might be a palliative resection and active adjuvant
therapyshould be given.
出处
《中华消化杂志》
CAS
CSCD
北大核心
1995年第4期206-208,共3页
Chinese Journal of Digestion
