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糖尿病患者的食管测压研究 被引量:8

ES0PHAGEAL MANOMETRIC STUDIES IN PATIENTS WITH DIABETES MELLITUS
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摘要 本文用标准食管测压术对随机选择的28例糖尿病患者进行了食管测压研究,并与12名健康志愿者作对照,发现多数无食管症状的糖尿病患者存在食管运动异常,表现为:食管下括约肌静息压力下降;食管体部下段收缩波幅降低;第三收缩、节段性收缩增加;双峰及多峰收缩增多。这些异常与患者的年龄、性别、病程、空腹血糖及糖基化血红蛋白水平、心脏植物神经和周围神经病变等无关。食管测压术是一种简便、可靠的方法,可用于早期检测糖尿病食管运动功能的异常。 Esophageal function was prospectively studied in 28 consecutive diabetes mellituspatients using the standard manometric technique,12 healthy volunteers served as control。Our data indicated that esophageal motilitv abnormalities could occur in absence ofesophageal symptoms in most diabetic patients. The abnormalities included:(1). resting loweresophageal sphincteric pressure diminished,(2)amplitude of contraction of lower segment ofesophageal body reduced,(3).the tertiary and segmental contraction increased,(4).doubleandmultiple-peak contractions more frequent.These abnormalities were irrelevant with patients’age, sex, course of illness, fasting blood sugar leve1,glycosylated hemoglobin level anddisordered autonomic nervous system of heart and peripheral neuropathy。Esophagealmanometry is simple, reproducible it can detect early esophageal motility dysfunction indiabetics。
出处 《中华消化杂志》 CAS CSCD 北大核心 1995年第4期200-202,共3页 Chinese Journal of Digestion
关键词 食管测压术 食管运动异常 糖尿病 Esophageal manometry Esophageal motility abnormalitis Diabetes melli-tus
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