摘要
用１７β－雌二醇为致癌剂，对去势雄性金黄地鼠以０．２ｍｇ／只皮下注射，每周一次，共２６周，总量５０ｍｇ／只．２６周时全部动物均发生肾细胞癌，肿瘤属混合细胞型，低度恶性，ＴＮＭ分期为Ｔ＿１Ｎ０Ｍ０－Ｔ＿２Ｎ０Ｍ０．其它器官无肿瘤发生。肿瘤组织病理学特征与人类肾细胞癌相似。
In the present experiment,the kidney tu-mors were induced by 17
beta-estradiol inmale Syrian golden hamsters within 6 months. Subcutaneous injections were
given with thedose 2.0 mg 17 beta-etradiol per animal dur- ing a period of 26 weeks, The total dose
of 17bate-estradiol is 52 mg per animal.The tumorswere characterized as mixed renal cell carcino-
ma with low maligancy,The charactertizationof TNM for every tumor was T N M to TNM. No
carcinoma were fund inanather organs.
出处
《中华实验外科杂志》
CAS
CSCD
北大核心
1995年第2期87-88,共2页
Chinese Journal of Experimental Surgery
