摘要
为了进一步了解体外冲击波碎石术（ＥＳＷＬ）对肾脏的远期影响，观察了２１只犬在ＥＳＷＬ后１、３、６及１２个月肾的肉眼、光镜和电镜的形态。结果显示：ＥＳＷＬ后１、３个月主要是肾小管的改变，但ＥＳＷＬ后６、１２个月时肾小管的病理改变不明显，而肾间质及肾小球的病理变化却逐渐明显，特别是肾小球系膜细胞胞浆中散在分布的肾素颗粒，表明ＥＳＷＬ后出现的高血压可能与所谓的“ｐａｇｅｋｉｄｎｅｙ效应”有关。
A thorough study of morphological changes in kidney was carried out in 21 dogs before and 1,3,6,and 12 months after ESWL.1 to 3 months after ESWL,the main site of monphological changes in kidney was the renal tubules.Whereas,6 and 12 months after ESWL,the main morphological changes were observed at the kidney glomeruli.Renin granules distributed in the mesangial cells of glomeruli have been observed suggesting that the wellknown“page kidney phenomenon“ might be responsible for the development of hypertension after ESWL.
出处
《中华泌尿外科杂志》
CAS
CSCD
北大核心
1995年第9期518-520,共3页
Chinese Journal of Urology
基金
卫生部科学研究基金
