摘要
对１６例甲状腺癌患者进行９９ｍＴｃ-甲氧基异了基异腈（ＭＩＢＩ）显像，以探讨其对甲状腺癌的诊断价值．方法：静脉注射９９ｍＴｃ-ＭＩＢＩ３７０ＭＢｑ后５～１５分钟和１～１．５小时分别采集早、晚期前位图像各１帧．计算早、晚期摄取比值（ＵＲ）和储留指数（ＲＩ）．结果：１６个甲状腺癌原发灶中１５个有放射性填充，而３１个甲状腺良性原发灶仅７个有放射性填充；７例有甲状腺癌淋巴结转移者显像均呈阳性．以晚期ＵＲ＞０．８０作为诊断甲状腺癌的下限值，诊断灵敏度、特异性和准确性分别为８７．５％、９３．５％和９１．５％，而肉眼观察仅分别为７１．４％、７７．４％和７５．６％．结论：甲状腺９９ｍＴｃ-ＭＩＢＩＥ显像对诊断甲状腺癌有临床意义，晚期ＵＲ值有助于提高诊断的灵敏度．
PURPOSE To evaluate the value of the thyroid 99mTc-MIBI imaging for detecting thyroid carcinoma.METHODS The early and late anterior images were acquired 5～ 15min and 1～ 1.5hr after injection of 370MBq 99mTc-MIBI. Then the early uptake rate (UR) and the retention index (RI) were calculated. RESULTS Radioactivity was Observed in 15 out of 16 primary thyroid carcinoma lesions, while in 31 thyroid benign lesions only 7 with radioactivity. The imaging results were all positive in 7 patients who had lymph node metastasis of thyroid carcinoma.If the late UR≥0.80 was taken as the threshold for detecting thyroid carcinoma, the sensitivity, specificity and accuracy were 87.5%, 93.5% and 91.5% respectively, while they were only 71.4%, 77.4% and 75.6% when estimated by the naked eyes. CONCLUSIONS The thyroid 99mTc-MIBI imaging has clinical significance in detecting thyroid carcinoma.The sensitivity of diagnosis may be increased by consulting the late UR values.
出处
《中华核医学杂志》
CAS
CSCD
北大核心
1995年第3期164-166,共3页
Chinese Journal of Nuclear Medicine
