摘要
对２３例小儿室管膜瘤进行了临床病理分析，其中男１７例，女６例，平均年龄８．８岁。２３例中肿瘤位于幕上者７例，幕下者１６例，术前平均病程分别为５．３个月和３个月。依据肿瘤的组织学特点，此瘤可分为乳头型（或粘液乳头型）、上皮型和多细胞型；依据肿瘤分化程度，可分为分化型和间变型室管膜瘤。２３例中有１７例胶质纤维酸性蛋白（ＧＦＡＰ）免疫组化染色呈阳性反应，其余６例为阴性。讨论了小儿室管膜瘤的临床病理特点、影响患者预后的因素及其组织学分类。
review of the clinicopathologic features of 23 ependymomas in children was made, of which 17 were male and 6 female,the male:female ratio beirig 2.8:1.Their average age was 8.8 years. Seven of the 23 ependymornas were supratentorial,16 were infratentorial. The mean duration of symptoms prior to operation in the two groups was 5.3 and 3 months respectively. Histologically,the tumor could be classified into three types:papillary(or myxopapillary),epithelial and cellular. According to the de-gree of differentiation, the tumor could be divided into typical ependymoma and anaplastic ependymo-ma. Immunohistochemically,17 of the 2 3 cases were positive for glial fiber acid protein(GFAP)and the remaining 6 cases were negative. The clinicopathologic features of childhood ependymomas,factors influencing prognosis and histologic classification are discussed.
出处
《中华病理学杂志》
CAS
CSCD
北大核心
1995年第6期369-371,共3页
Chinese Journal of Pathology
