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支气管动脉灌注化疗加体外照射治疗晚期肺癌37例 被引量:8

Bronchial Artery Infusion of Chemotherapeutic Agents Plus External Irradiation in the Treatment of Advanced Lung Cancer──A Report of 37 Cases
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摘要 1990年2月至1993年12月,选择性支气管动脉灌注化疗(BAI)加体外放射治疗(RT)37例不能手术的晚期肺癌(Ⅲ期33例,Ⅳ期4例),经治疗90.1%的病例症状消失或减轻,近期有效率(CR+PR):单用BAI疗法为70.3%,BAI+RT为89.2%。随访至1994年5月,生存12例,生存期4~48个月,死亡25例,其中位生存期12个月,平均14.4个月。全组病例0.5、1、2、3年生存率分别为94.4%、61.3%、37.5%及6.3%。对不能手术的晚期肺癌,BAI合并放疗是一种选择的治疗方法。 Between February 1990 and December 1993, 37 patients with advanced lung cancer (stage Ⅲ 33 cases,stage Ⅳ 4 cases) were treated with bronchial artery infusion chemotherapy (BAI) plus external radiotherapy (RT). Symptomatic relief was observed in 90.1% of patients. Remission rates (CR+PR) was 70.3% for those treated with BAI alone and 89.2% in patients treated with BAI+RT. Followup for 4 to 48 months demonstrated that 12 patients in this series are still living and 25 patients died, with a median survival period of 12 months. The overall 0. 5-, 1-, 2-and 3-year survival rates for all patients were 94.4%, 61.3%, 37.5% and 6.3% respectively. It is indicated that BAI plus RT, being safe and effective, is the treatment of choice for patients with unresectable lung carcinoma.
出处 《中国肿瘤临床》 CSCD 北大核心 1995年第8期554-557,共4页 Chinese Journal of Clinical Oncology
关键词 支气管动脉灌注 肺肿瘤 放射疗法 药物疗法 Advanced lung cancer Bronchial artery infusion Chemotherapy Radiotherapy
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