摘要
目的:探讨等离子低温射频软腭打孔消融对阻塞性睡眠呼吸暂停低通气综合征的临床疗效。方法:对6 5例经多导睡眠图监测确诊为阻塞性睡眠呼吸暂停低通气综合征的患者行软腭等离子低温射频打孔消融术,缩短软腭及悬雍垂。结果:术后随访3～6个月,患者均取得了满意效果。患者射频治疗前和治疗12周后多导睡眠参数比较显示:治疗后Ⅰ+Ⅱ期睡眠时间明显缩短,Ⅲ+Ⅳ期睡眠时间明显延长,睡眠效率及最低脉氧饱和度(LSpO2 )均显著提高(P <0 .0 5 ) ;呼吸暂停低通气指数减低及打鼾时间缩短与治疗前相比差异非常显著(P <0 .0 1)。患者射频治疗12周后软腭长度及悬雍垂长度的缩短及鼾声评级的降低均较治疗前有显著差异(P <0 .0 1)。Epworth嗜睡程度评分亦较治疗前明显降低(P <0 .0 1)。结论:等离子低温射频软腭打孔消融对于轻度OSAHS患者具有较好的近期疗效,且方便、安全、微创、康复快,无不良反应,有较好的发展前景,值得推广应用。
Objective: To investigate the clinical efficacy of soft palate ablation with plasma radiofrequency on obstructive sleep apnea hypopnea syndrome(OSAHS). Method:Sixty-five patients polysomnographically proved mild OSAHS were given radiofrequency ablation to their soft palates. The polysomnography examinations were carried out before and 12 weeks after radiofrequency operation respectively. The length of soft palate and uvula, snoring scale and Epworth sleepiness score(ESS) were also compared. Results:Followed-up from 3 to 6 months, polysomnography parameters before and 12 weeks after radiofrequency operation showed that Ⅰ+Ⅱphase sleep time shortened significantly, Ⅲ+Ⅳphase sleep time prolonged, sleep efficiency and the lowest pulse oxygen saturation improved significantly. In addition, there were significant differences in the decrease of apnea hypopnea index after operation(P<0.05). 12 weeks after treatment, the length of soft palate and uvula shortened, snoring scale and ESS decreased significantly(P<0.01). The pain by speech and swallow was mild 1～3 days after operation, and obvious further improvement could be detected 7 days after operation. Conclusion: Plasma radiofrequency ablation at low temperature is effective to mild OSAHS at least in a short term. This treatment is convenient,simply safe and minimally invasive without obvious adverse reactions, and it is worthy to be popularized.
出处
《山东大学基础医学院学报》
2005年第3期139-141,共3页
Journal of Preclinical Medicine College of Shandong Medical University
