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MEG和EEG在癫痫治疗中的作用 被引量:1

MEG and EEG in epilepsy therapy
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摘要 脑电图(EEG)只能选择性地探测切线位的电源,而脑磁图(MEG)可以同时测量切线和径向的电活动,两者均可独立提供其他神经影像学方法所无法提供的神经生理学数据。当执行多导联的任务时,MEG检查时间远少于EEG所需,且精确性更佳,而EEG的优势在于长程视频监测。因此,MEG和EEG在癫痫检查中可互为补充,两者分析结果与侵入性电极获得的结果相比无明显差异。头皮EEG可提供丰富的信息,但考虑外形非规则和内容物导电率的不均一性,构建EEG头颅模型变得十分困难。因此在同样使用标准半球模型情况下,MEG信号偶极子定位方法要比EEG偶极子定位方法优越。然而,如果使用拟和度好的头颅模型并加强EEG信号的分析,EEG定位的精确性和MEG相比较并无明显区别。目前,研究的重点是联合使用全脑MEG和多导联EEG,并发展更佳的源模型技术。 Both electroencephalogram (EEG) and magnetoencephalogram (MEG) provide unique neurophysiologic data not obtainable by other neuroimaging techniques.MEG has now emerged as a mature clinical technology. While both EEG and MEG can be performed with more than 100 channels, MEG recordings with 100 to 300 channels are more easily done because of the time needed to apply a large number of EEG electrodes. EEG has the advantage of the long-term video EEG recordings. MEG and EEG seem to complement each other for the detection of interictal epileptiform discharges. MEG selectively detects tangential sources. EEG measures both radial and tangential activity, although the radial components dominate the EEG signals at the scalp. Thus, while EEG provides more comprehensive information, it is more complicated to model due to considerable influences of the shape and conductivity of the volume conductor. Dipole localization techniques favor MEG due to the higher accuracy of MEG source localization compared to EEG when using the standard spherical head shape model. However, if special care is taken to address the above issues and enhance the EEG, the localization accuracy of EEG and MEG actually are comparable. The combined use of whole-head MEG systems and multichannel EEG in conjunction with advanced source modeling techniques is an area of active development and will allow a better noninvasive characterization of the irritative zone in presurgical epilepsy evaluation.
出处 《东南大学学报(医学版)》 CAS 2005年第4期280-283,共4页 Journal of Southeast University(Medical Science Edition)
关键词 癫痫 脑电描记术 脑磁图描记术 综述[文献类型] epilepsy seizures magnetoencephalography electroencephalography review[publication type]
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