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药物胃肠道吸收屏障及新型促吸收方法 被引量:9

Intestinal absorption barrier and novel strategies for absorption enhancement
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摘要 胃肠道屏障是机体的重要保护系统,可阻止毒物及抗原的吸收,但也是限制药物吸收的主要因素,导致许多药物的口服生物利用度低,同时也是造成许多具有较好生物活性的候选化合物不能进入后续开发研究的根本原因.
作者 李静 王广基
出处 《药学学报》 CAS CSCD 北大核心 2005年第7期600-605,共6页 Acta Pharmaceutica Sinica
基金 国家高技术研究发展计划(863计划)资助项目(2003AA22347A) 江苏省药物代谢动力学重点实验室资助项目(BM2001 201).
关键词 肠道 吸收屏障 促吸收 intestinal absorption barrier absorption enhancement
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