摘要
目的探讨肝癌介入治疗引起急性肾功能衰竭(ARF)的原因、临床表现特点、治疗及预防。资料与方法对3例肝癌患者因介入治疗所致ARF的临床表现、实验室检查、治疗及转归进行回顾性分析、讨论。结果3例肝癌均为巨块型(直径分别为10.5cm、13.4cm、11.9cm),介入治疗后出现ARF的时间分别为术后第1d、第2d、第4d。经以血液透析为主的临床综合治疗后3例患者肾功能均恢复正常。结论肝癌介入治疗引起ARF的比例虽然较小,但仍应引起重视。术前对适应证进行严格控制、术中合理的栓塞化疗用药、术后积极有效的临床观察与治疗可减少介入治疗后ARF的发生率,一旦发生,及时进行血液透析是治疗的关键。
Objective To discuss the clinical features and the pathogenesis of transcatheter arterial chemoembolization (TACE)-induced acute renal failure(ARF), and its treatment, prevention. Materials and Methods Clinical features, treatment process and laboratory findings of 3 patients suffered from primary liver cancer with TACE-induced ARF were analyzed retrospectively.Results 3 cases of primary liver cancer, presented as massive type. The maximum size of lesions were 10.5cm, 13.4cm, 11.9cm respectively. ARF were occurred 1、2、4 days after TACE in different case. All patients were managed with hemodialysis simultaneously and got over soon.Conclusion TACE can induce acute renal failure, although ARF in patients with liver cancer after TACE is uncommon. The possibility of TACE-induced ARF will be decreased when indications should be selected strictly, reasonable medication and renal function should be closely monitored in the susceptible patients. Hemodialysis is key for the treatment.
出处
《临床放射学杂志》
CSCD
北大核心
2005年第7期631-633,共3页
Journal of Clinical Radiology
关键词
巨块型肝癌
介入治疗
急性肾功能衰竭
血液透析
Transcatheter arterial chemoembolization Hepatic cancer Acute renal failure Analysis
