摘要
结直肠癌是常见的恶性肿瘤之一,有关其检测的肿瘤标记物很多,部分已广泛应用于临床。但是,迄今为止尚无理想的肿瘤标记物。本文简单介绍几种常用的血清学肿瘤标记物例如癌胚抗原、CA19-9、CA50、CA242等对结直肠癌的诊断价值,并探讨近来研究发现的几种联合检测方法对提高结直肠癌诊断正确性的临床价值。另外,随着分子生物学技术的发展,新的肿瘤标记物及基因肿瘤标记物对结直肠癌诊断的研究也取得较大的进展,有望成为提高结直肠癌诊断效率的新的检查方法。
Colorectal cancer is one of the most common malignant tumors. There are many tumor markers for detecting colorectal cancer, some of which have been widely used in clinical area. However, still lack an ideal tumor marker of colorectal cancer. In this review, we simply characterized some com-mon tumor markers including carcinoembryonic antigen, CA19-9, CA50, CA242 etc and their dignostic value. And here we discussed some combined detecting procedures which improve diagnostic accuracy of colorectal cancer. In addition, with the development of the biomoleculer technique, some newly discovered tumor markers and genetic marekers have gained great progress in the research of colorectal cancer, and will become a promissing technique in the diagnosis of colorectal cancer.
出处
《国外医学（放射医学核医学分册）》
2005年第3期101-104,共4页
Foreign Medical Sciences(Section of Radiation Medicine and Nuclear Medicine)
