超顺磁氧化铁在心血管MRI中的应用
摘要
磁共振成像技术发展迅速,其在心血管领域中的应用越来越受到人们重视。近几年一种新兴的对比剂超小型超顺磁氧化铁成为MRI研究的热点。文中详细介绍其在冠脉成像、缺血及再灌注心肌显像、动脉粥样硬化及外周血管等领域中动物实验与临床应用现状,阐述了其潜在的巨大临床价值。
参考文献23
-
1Weinmann HJ, Brasch RC, Press WR,et al. Characteristics of gadolinium-DTPA complex: a potential NMR contrast agent.AJR, 1984,142(3):619-624. 被引量:1
-
2Dirksen MS, Lamb HJ, Kunz P,et al. Improved MR coronary angiography with use of a new rapid clearance blood pool contrast agent in pigs. Radiology,2003,227(3):802-808. 被引量:1
-
3Wang YX, Hussain SM, Krestin GP. Superparamagnetic iron oxide contrast agents: physicochemical characteristics and applications in MR imaging. Eur Radiol,2001,11 ( 11 ):2319-2331. 被引量:1
-
4Chouly C,Pouliquen D,Lucet I,et al.Development of superparamagnetic nanoparticles for MRI: effect of particle size, charge and surface nature on biodistribution. J Microencapsul, 1996,13(3):245-255. 被引量:1
-
5Taylor AM, Panting JR, Keegan J,et al. Safety and preliminary findings with the intravascular contrast agent NC100150injection for MR coronary angiography. J Magn Reson Imaging,1999,9(2):220-227. 被引量:1
-
6Simonsen CZ, Ostergaard L, Vestergaard-Poulsen P,et al. CBF and CBV measurements by USPIO bolus tracking:reproducibility and comparison with Gd-based values. J Magn Reson Imaging, 1999,9(2):342-347. 被引量:1
-
7Chambon C, Clement O, Le Blanche A,et al. Superparamagnetic iron oxides as positive MR contrast agents: in vitro and in vivo evidence. Magn Reson Imaging, 1993,11(4):509-519. 被引量:1
-
8Stillman AE, Wilke N, Jerosch-Herold M. Use of an intravascular T1 contrast agent to improve MR cine myocardialblood pool definition in man. J Magn Reson Imaging, 1997,7(4):765-767. 被引量:1
-
9Bunce NH, Moon JC, Bellenger NG,et al. Improved cine cardiovascular magnetic resonance using Clariscan (NC100150injection). J Cardiovasc Magn Reson,2001,3(4):303-310. 被引量:1
-
10Taupitz M, Schnorr J, Wagner S,et al. Coronary MR angiography: experimental results with a monomer-stabilized blood pool contrast medium. Radiology,2002,222(1):120-126. 被引量:1
-
1黄力,王宁霞,刘斯润.SPIO在肝脏占位病变MRI诊断中的作用[J].实用放射学杂志,2000,16(11):641-643. 被引量:12
-
2贾暮云,袁荣涛,李玉军.颌面部海绵状血管瘤的临床分型与治疗[J].齐鲁医学杂志,1998,13(1):28-29. 被引量:2
-
3姜保东,冯晓源.采用超顺磁氧化铁作为磁共振对比剂活体示踪移植的神经干细胞[J].国外医学(临床放射学分册),2005,28(5):273-276. 被引量:1
-
4许如意,高连如,张宁坤,汪兆艳.骨髓间充质干细胞的培养和超顺磁氧化铁标记[J].海军总医院学报,2008,21(3):129-132.
-
5周斌,于春鹏,李丹,姜在波,钱结胜,朱康顺,庞鹏飞,单鸿.大鼠骨髓间充质干细胞的超顺磁氧化铁颗粒标记及MR成像[J].中国医学影像技术,2008,24(12):1879-1882. 被引量:8
-
6周晟.磁共振成像技术(MRI)在宫颈癌分期及治疗中的临床价值[J].中外医疗,2012,31(34):160-161. 被引量:4
-
7郭香伟.磁共振成像在诊断和评价宫颈癌分期中的应用[J].河南职工医学院学报,2014,26(3):296-297. 被引量:3
-
8殷敏敏,余永强,黄薇园,钱银锋.大鼠C6脑胶质瘤超小型超顺磁氧化铁灌注成像与Gd-DTPA灌注成像对比[J].中国医学影像技术,2011,27(3):444-448. 被引量:2
-
9林江.心血管系统MRI检查技术的进展[J].中国临床医学,2004,11(2):135-138.
-
10王瑛,叶素敏,陈绮璐,张晓云,黄帼英,刘再毅.超声辐照联合微泡增强介导SPIO标记ADSCs及细胞内铁蛋白表达[J].贵阳医学院学报,2013,38(2):141-144.