摘要
目的评价三维适形放疗对术后局部复发或转移的结直肠癌患者局部控制率和生存率的影响。方法23例术后局部复发或转移的结直肠癌患者采用三维适形放疗,5～7Gy/次,隔日1次,共6～8次,总剂量DT40～45Gy。结果完全缓解率为35%(8/23),部分缓解率为39%(9/23),有效率为74%(17/23)。1、2、3年生存率分别为78%、52%、30%。结论三维适形放疗可提高术后局部复发或转移结直肠癌的控制率和生存率,改善其生存质量。
Objective To evaluate the effects of three-dimensional conformal radiation therapy (3DCRT) on the local control and survival of patients with local recurrence or metastasis in colorectal cancer. Methods Twenty-three patients with local recurrence or metastasis in colorectal cancer were irradiated by 3DCRT. The regimen was: total dose 40-45?Gy, 5-7?Gy/f, 1f/2d. Results Of the 23 patients, 8 achieved CR and 9 PR with a total response rate of 74%(17/23). The overall 1-, 2-and 3-year survival rates were 78%,52% and 30%. Conclusion 3DCRT is able to prolong the survival and improve the life quality of patients with local recurrence or metastasis in colorectal cancer.
出处
《中华放射肿瘤学杂志》
CSCD
北大核心
2005年第4期302-303,共2页
Chinese Journal of Radiation Oncology
关键词
结直肠癌
局部复发
肿瘤转移
三维适形放疗
放射疗法
Neoplasm recurrence, local
Neoplasm metastasis
Colorectal neoplasms
Radiotherapy, conformal
Prognosis
