摘要
用１ｍｏｌ／ＬＮｏＯＨ溶液造成家兔角膜实验性碱烧伤模型。碱烧伤后第１、３、７和１４天的角膜超微结构和蛋白聚糖（以钌红即ＲＲ颗粒表示）数量及分布的变化表明：（１）碱烧伤后第１天，用膜上皮和内皮脱落；轻度碱烧伤后第３～７天，角膜上皮开始再生。（２）角膜基质层的胶原纤维变得松散而不整齐。随着碱烧伤的康复，胶原纤维又逐渐趋于致密和整齐。（３）角膜碱烧伤后ＲＲ颗粒减少。轻度碱烧伤后第７天，ＲＲ颗粒增多井逐渐超过正常水平。当碱烧伤基本康复时，ＲＲ颗粒减少至接近正常水平。
AbstractArabbit model of alkali burned cornea was made with 1 mol/L NaOH. On days 1,3,7 and 14 after theburn,changes in ultrastructure and the ruthenium red(RR) proteoglycan granules were as follows:(1) Theepithelium and endothelium peeled off within day 1. Inlightly burned cases,the epithelium regenerated ondays 3-7;(2) The collagen fibers of corneal stromabecame loose and irregular after the burn and began torecover with recovery of the cornea;(3)TheRR pro-teoglycan granules decreased markedly after the burn,in light cases they increased on day 7 and gradually ex-ceeded the normal amount,and tben they reap-proached the normal when the cornea was essentiallyrecovered.
出处
《中华眼科杂志》
CAS
CSCD
北大核心
1994年第4期305-307,T035,共4页
Chinese Journal of Ophthalmology
