摘要
作者使用波长１．０６μｍＮｄ：ＹＡＧ激光，对１２只成年杂种犬经腹腔进行了椎间盘（Ｌ＿３～６）的汽化研究。术后按计划如期将动物处死取材进行椎间盘的组织学观察。结果表明：至预定处死期前无１例出现肢体运动及括约肌功能障碍。光镜下，术后即刻椎间盘内空腔形成，空腔边缘可见纤维环、软骨终板及部分椎体松质骨断面。术后２～８周空腔被肉芽组织及纤维组织所充填。术后１２～４０周空腔内纤维组织则为软骨组织所取代。在本研究及以往尸体标本研究的基础上，作者于１９９３年３月将经皮激光椎间盘减压术（ＰＬＤＤ）技术应用于临床，首批治疗腰椎间盘突出症１０例，平均随访３个月，按Ｍａｃｎａｂ疗效评定标准，本组优７例、良３例，近期疗效满意。
AbstractThe lumbar intervertebral discs(L_3～6)were ablat-ed through a transperitoneal approach in 12 adult dogsby usiiig Nd: YAG Iaser(1.06μm) with a 600μmquarz fiber. The status of limbs motion and spliincter(bladder,bowel) was observed for evaluating the safe-tv of laser irradiatin. After irradiation,the animalswere sacrificed at prescribed intervals of up to40 weeks(2、4、8、12 and 40 weeks after operation).The lumbarintervertebral discs were harvested and suhected tolight microscopic observation. No dog had sufferedfrom neurogenic dysfunction of limb motion andsphincter. Histological findings immediately after theirradiation showed the disc was vaporized and a cavitywas made, After 2 and 4 weeks, fibrous tissues beganto pro11ferate , but cartilaginous tissues replaced the fi-brous tissues 12 weeks after thelaser irradiation. Nonew bone formation was found within 40 weeks afteroperation。 On thebasis of this study and our previouscadaveric study , percutaneous laser disc decompression(PLDD ) was applied in clinical practice in march of1993.10 patients underwent PLDD utilizing the samelaser equipment. The average follow-up was 3months.According to the Macnab’ s criteria, therewas an excellent response in 7 patients and a good re-sponse in 3.
出处
《中华外科杂志》
CAS
CSCD
北大核心
1994年第3期187-189,T023,共4页
Chinese Journal of Surgery
