摘要
观察双侧卵巢切除和肌注雌二醇对雌性成龄脉鼠鼻粘膜的组织形态学影响。发现双侧卵巢切除的豚鼠的鼻粘膜呈退行性改变，包括纤毛崩解、脱落和腺体萎缩。肌注雌二醇豚鼠的鼻粘膜则表现为粘膜增厚，粘膜上皮下组织疏松和水肿，腺体增生，纤毛密集。提示不同水平雌激素对鼻粘膜有不同的作用。
The histomorphological influences of ovariectomies and estradiol injections on the nasal mucosa were observed in adult female guinea pigs.In the mucosa of ovariectomized guinea pigs,degenerative changes including dissolving and desquamation of cilia and glandular hypotrophy were found.On the contrary,thickening layer of the epithelium,spongiosis and edema of the corium,hyperplasia of glands and increased density of cilia were observed in the mucosa of guinea pigs receiving estrogen. The results demonstrated that different levels of estrogen might have differents effects on the nasal mucosa.
出处
《中华耳鼻咽喉科杂志》
CSCD
1994年第2期98-100,T015,共4页
Chinese Journal of Otorhinolaryngology
基金
国家自然科学基金
