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肿瘤抗原NY-ESO-1研究进展

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摘要 肿瘤抗原NY-ESO-1是肿瘤-睾丸(cancer-testis,CT)抗原,其编码基因是一基因家族,目前发现的主要包括NY-ESO-1、LAGE-1和ESO3三个成员。NY-ESO-1是迄今发现的最具免疫原性的肿瘤抗原之一,可以在NY-ESO-1表达阳性的肿瘤患者体内引起自发性体液免疫反应和T细胞免疫反应,因此在抗原特异性肿瘤免疫治疗中具有广泛的应用前景。
出处 《国外医学(免疫学分册)》 2005年第4期209-212,共4页 Foreign Medical Sciences(Section of Immunology Foreign Medical Sciences)
基金 上海市自然科学基金资助项目(03ZR14041)
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