摘要
目的 探讨高原失血性休克兔,用不同浓度的氧合兼输液对其血气和血管紧张素Ⅱ的影响。方法 4 2只家兔分6组,在模拟35 0 0m高原低压舱内,放血,并维持血压在4 0mmHg 1h ,后用不同浓度氧合并输2倍于失血量的平衡液治疗,另设对照组。在休克前、后不同时相点分别采集血样,测动脉氧分压,HCO-3 、血管紧张素Ⅱ含量,并观察动物急性死亡情况。结果 用80 %氧合并输液的一组动物存活时间最长、4h存活率最高。血管紧张素Ⅱ在休克后明显升高,但氧疗后无明显变化。结论 对高原失血性休克兔需用较高浓度氧疗合并输液复苏。氧疗对血管紧张素Ⅱ并没有明显影响。
Objective To study the effects of oxygen with different concentration and fluid transfusion on the blood gas and angiotensinⅡ of the hemorrhagic shock rabbits in high altitude Methods To divide 42 rabbits into 6 groups, bleed them in the simulated 3 500 m high altitude stratochamber, and maintain the blood pressure in 40 mm Hg 1 h, then cure them with equilbrium liquid in different concentration which is twice than blood loss, and make additional contrast group. To sample blood in different periods before and after shock, determine the arterial partial pressure, HCO - 3, angiotensin Ⅱ, and then observe the animal acute death. Result The living time and livability in 4 h of rabbits are highest by 80% oxygen with fluid transfusion. AT Ⅱ raise obviously after shock, but no change after oxygen therapy. Conclusion It can resuscitate the hemorrhagic shock rabbits in high altitude by oxygen with higher concentration and fluid transfusion. It has no significant influence to AT Ⅱ by oxygen therapy.
出处
《中国实用护理杂志》
2005年第6期1-3,共3页
Chinese Journal of Practical Nursing
基金
"十五"军队重点课题科研基金资助项目 (编号 :0 1Z10 0 )
