摘要
目的观察重度急性一氧化碳中毒(ACOP)患者血清肌酸激酶脑型同功酶(CKBB)动态变化及意义。方法20例重度ACOP患者当天及中毒后3,5,7,10,14,21,30d分别取静脉血检测CKBB,并与正常对照组进行对照。结果20例患者血CKBB在急性期逐渐升高,2～3周时达到高峰,后逐渐下降,1个月时降至正常。本组有2例中毒后第28天和第29天发生ACOP迟发性脑病(DEACMP),其CKBB不但不降,反而继续升高,发生迟发脑病后仍高于正常值7～8倍。结论动态观察ACOP患者血CKBB的变化有助于DEACMP的早期诊断。
Objective To observe the dynamic changes of serum creatine kinase BB (CK-BB) content in patients with severe acute carbon monoxide poisoning (ACOP).Methods The serum CK-BB contents were measured by electrophoresis in 20 patients with severe ACOP on the 1st,3rd,5th,7th,9th,10th,14th,21st and 30th day after poisoning and compared with those in 10 healthy adults.Results The serum contents of Ck-BB rose gradually, reached the peak during the 2nd-3rd weeks, and returned to normal on the 30th day after poisoning. Two of the patients suffered from delayed encephalopathy respectively on the 28th and the 29th day after poisoning and their serum contents were 7～8 times higher than normal. Another two patients with delayed encephalopathy were transferred to our hospital on the 21st and 25th day after poisoning,respectively, whose serum contents were much higher than those of the healthy adults. Conclusions Delayed encephalopathy after acute monoxide poisoning can be early diagnosed by observing the dynamic changes of serum CK-BB content in patients with ACOP.
出处
《中华航海医学与高气压医学杂志》
CAS
CSCD
2005年第2期75-77,共3页
Chinese Journal of Nautical Medicine and Hyperbaric Medicine
基金
北京市重点学科资助(1999卫科扶字03)
