摘要
１９９１年１１月～１９９３年７月对３７例苯丙酮尿症（ＰＫＵ）患儿智商进行测定，发现７３％ＰＫＵ患者在语言、精细动作发育方面落后于大运动。＜６个月早治组发育商（ＤＱ）为９５．８６±８．５，＞６个月晚治组ＤＱ为７２．０８±２０．３４，两组比较有极显著差异（Ｐ＜０．０１）。晚治组治疗后ＤＱ较治疗前有明显提高，治疗前后相比有显著性差异（Ｐ＜０．０５）。对其中３名智力异常患者儿进行早期干预６个月，干预后的发育商、年智龄增长速度、精细动作及语言均有明显提高（ＤＱ增加约１３～２１）。说明对ＰＫＵ患儿的早期诊断、早期治疗、早期干预是非常必要的。
Thirty- seven patients with phenylketonuria,aged from six months to five years old, were examined by intelligence test from November,1991 to July,1993.The results show language and fine motor fall behind gross motor in 73%patients. The DQ in the early treated group(<6m)was 95.86±8.5,the DQ in the late treated group was 72.08 ±20.34(P<0.01).After treatment,the DQ in the late treated group was significantly increased as compared with that before treatment(P<0.05).Early intervention was tak-en to three children for half year,Their DQ and Mental Age in year were singnificantly el-evated(DQ elevated 13～21).Their behavior funtions in language and fine motor were al- so improved. Early diagnosis,treatment and intervention to PKU children are necessary.
出处
《中日友好医院学报》
1994年第3期151-154,共4页
Journal of China-Japan Friendship Hospital
关键词
发育
早期干预
苯丙酮尿症
儿童
developmental quotient
early intervention
phenylketonuria
