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颅咽管瘤术后的中枢性低钠血症及治疗 被引量:6

Therapy of central hyponatremia after surgery of craniopharyngioma
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摘要 目的:探讨颅咽管瘤切除术后水钠平衡紊乱的临床特点及治疗方法,总结颅咽管瘤术后中枢性低钠血症的诊断和治疗经验,对抗利尿激素不适当分泌综合征与脑性盐耗综合征进行鉴别。方法:回顾性分析颅咽管瘤术后中枢性低钠血症患者30例。结果:该组患者术后均出现尿量增多,低血钠、高尿钠、循环血量减少,临床表现及实验室检查均支持脑性盐耗综合征诊断,全部患者血钠得以纠正。结论:颅咽管瘤术后中枢性低钠血症发生率较高,且多为脑性盐耗综合征。低血钠、高尿钠及意识状态改变是中枢性低钠血症的诊断依据,抗利尿激素不适当分泌综合征应限水治疗,脑性盐耗综合征则应补水和补盐治疗。 Objective:To study the clinical characterization and effective treatment of the patients with the water and blood sodium disorders after resection of craniopharyngioma and conclude the experiences of central hyponatremia in post-operative patients. Differentiate SIADH from CSWS.Methods:30 post-opertive patients with central hyponatremia were retrospectively analyzed.Results: Hyponatremia, hydrouria and volume depletion were rectificated in all patients diagnosed as cerebral salt wasting syndrome. Conclusion:Central hyponatremia, especially CSWS are frequently seen after craniopharyngioma surgery. Hyponatremia, hypernatruria and variation of conscious state are diagnostic criteria of central hyponatremia. The appropriate treatment of cerebral salt wasting, fluid and salt replacement, is opposite from the usual treatment of hyponatremia caused by inappropriate secretion of antidiuretic hormone.
出处 《军医进修学院学报》 CAS 北大核心 2005年第3期188-190,共3页 Academic Journal of Pla Postgraduate Medical School
关键词 颅咽管瘤 低钠血症 抗利尿激素 分泌不当综合征 中枢性 脑损伤 craniopharyngioma hyponatremia inappropriate ADH syndrome(SIADH)
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二级参考文献1

  • 1N. Aoki,T. C. Origitano,O. Al-Mefty. Vasospasm after resection of skull base tumors[J] 1995,Acta Neurochirurgica(1-3):53~58 被引量:1

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