摘要
目的:研究环境香烟烟雾(ETS)对机体内微量元素的影响。方法:大鼠30只,随机均分为3组:染毒1h组、染毒2h和对照组。比较测定血清、大脑、肝脏和甲状腺组织Cu、Zn及Se含量。结果:大鼠连续染毒6w后,血清中Cu含量低于对照组(P<0.05);而肝脏中Cu及甲状腺中Zn的含量明显高于对照组(P<0.01);脑组织和肝脏中Se含量显著低于对照组(P<0.01);脑组织中Zn含量显著低于对照组(P<0.01);1h染毒组和2h染毒组相比较,血清和甲状腺Cu、肝脏和大脑Zn及大脑Se含量差异均有显著性(P<0.05或P<0.01)。结论:ETS可影响大鼠血液和脏器中微量元素Cu、Zn、Se含量,影响程度与染毒剂量有关。
Objective: To study the effects of environmental tobacco smog on trace ele- ments in rat. Methods:Thirty rats were randomly divided into 3 groups (exposed 1 hour,exposed 2 hour and control group). The contents of Cu、Zn and Se in serum、brain、liver and thyroid gland were mensurated respectively. Results: After being exposed for 6 weeks,the Cu level in serum and thyroid and the Zn level in brain were lower than those of control (P<0.05). The Se levels in brain,liver and thyroid were also lower than that of controls (P<0.01). However,the Cu level in liver,the Zn level in thyroid were higher than thoses of control (P<0.01). Compared with the two exposed groups,the Cu levels in serum and thyroid,the Zn levels in liver,and brain, the Se level in brain were all significantly changed (P<0.05 or P<0.01). Conclusion:ETS can change the levels of Cu, Zn and Se in blood and organs of exposed rats. The degree of effects are related with dose of exposed.
出处
《温州医学院学报》
CAS
2005年第3期187-189,共3页
Journal of Wenzhou Medical College
