摘要
目的:探讨成牙本质细胞的发育变化以及牙本质的结构发育特点。方法:取不同日龄新生大鼠的下颌切牙牙胚进行光、电镜观察。结果:成牙本质细胞由低柱状变为高柱状,并发生极化,细胞器渐增多,有分泌颗粒出现,细胞突起逐渐形成;形成的前期牙本质和牙本质在6～9d达最厚,且胶原纤维较丰富而密集,牙本质小管多;成牙本质细胞突起贯穿前期牙本质和牙本质,并进入牙釉质中。结论:0～9d日龄大鼠的下颌切牙牙胚正处于牙体组织的分泌形成期,是研究牙齿发育过程的很好的动物模型。
Objective: To explore the developing changes of structure in odontoblasts and dentin. Methods: Light and electronic microscopy were used. The lower incisor germs of mice were made into sections. Results: The shapes of odontoblasts of neonatal mice were different from short column to high column. Cell polarization was also found, and organellae increased. Thickest dentins were observed in mice of 6 to 9 days old. There was a lot of collagen and dentinal tubules in dentin. The processes of odontoblasts were from dentin to predentin, and then to enamel. Conclusion: The lower incisor germs of 0 to 9 days old mice were at secretory and formative period of tooth tissues, and this kind of mice were good animal models for study of tooth development.
出处
《中国医科大学学报》
CAS
CSCD
北大核心
2005年第3期229-230,共2页
Journal of China Medical University
