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重组人类促红细胞生成素防治早产儿贫血的临床分析 被引量:1

Evaluation of clinical efficacy of domestic made recombinant human erythropoietin in preventing and treating anemia in preterm infants
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摘要 Objective To evaluate the efficacy of erythropoietin in prevention and treatment of anemia of prematurity. Methods 119 preterm infants were randomly assigned to receive (treated group,60 neonates) or not to receive(control group, 59 neonates) rhEPO. RhEPO (750IU·kg -1·w -1)was given three times weekly for 4 weeks.Both these two groups received iron and folic acid.Results Treated group had a marked increase of reticulocyte compared with the control group (P<0.01).There were statistically significant differences between these two groups in the rate of weight gain(P<0.05).Condusion Early administration of high dosage of rhEPO can lighten the degree of anemia in Objective To evaluate the efficacy of erythropoietin in prevention and treatment of anemia of prematurity. Methods 119 preterm infants were randomly assigned to receive (treated group,60 neonates) or not to receive(control group, 59 neonates) rhEPO. RhEPO (750IU·kg -1·w -1)was given three times weekly for 4 weeks.Both these two groups received iron and folic acid.Results Treated group had a marked increase of reticulocyte compared with the control group (P<0.01).There were statistically significant differences between these two groups in the rate of weight gain(P<0.05).Condusion Early administration of high dosage of rhEPO can lighten the degree of anemia in neonate
出处 《云南医药》 CAS 2005年第3期219-220,共2页 Medicine and Pharmacy of Yunnan
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