摘要
1978年6月至1993年12月,我院完成同种异体肾移植969例,1011例次。人/肾总存活率1年为89.2%/78.7%;3年为82.0%/74.7%;5年为67.0%/58.4%;存活10年以上已有12例,最长存活已达15年。15年的经验表明:(1)高质量取肾与植肾手术尤为重要;(2)由于环孢素在体内的吸收和代谢存在着明显个体差异及受者免疫反应强弱不同,监测环孢素血浓度甚为重要;(3)应坚持ABO血型及淋巴细胞毒性试验配型工作;(4)感染仍是移植失败的重要原因,应将预防感染措施贯彻于术前、术中及术后的全过程;(5)加强肾移植随诊工作,指导康复期的治疗。
renal allograft transplants in 969 cases were performed in 15 years, from June, 1978 to December,1993.Patients/grafts survival rates were 89. 2%/78. 7% for 1 year, 82. 0%/74. 7% for 3 years and 67. 0%/58. 4% for 5 years respectively. Twelve cases have survived for more than 10 years. Expereience in renal transplantation in the past 15 years revealed: (1)High quality of procurement and transplantation was of the most important. (2) The monitoring of CsA blood level ABO matching and lymphocytes toxicity assay should be stillpersistent. (3) Infections were the main cause of failure in transplantation. Prevention of infections should be carried out before, after and during operation. (4)Follow-up and directing the treatment during convalescent period must be emphasized.
出处
《中华器官移植杂志》
CAS
CSCD
1994年第4期146-148,共3页
Chinese Journal of Organ Transplantation