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139例胰岛素依赖型糖尿病发病方式的分析 被引量:2

INVESTIGATION OF THE FORM OF ONSET IN 139 CASES OF INSULIN-DEPENDENT DIABETES MELLITUS
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摘要 对139例胰岛素依赖型糖尿病(IDDM)病人进行回顾性研究。男性54例,女性85例。平均年龄31.74±12.20岁。平均病程13.46±9.15年。48例在发病前有明确病毒感染史(占34.5%),其中以上呼吸道和肠道感染占绝大多数(83%),2例在接种卡介苗后发生IDDM。病毒感染与是否首发为糖尿病酮症酸中毒(DKA)无关。有病毒感染组平均发病年龄15.58±10.04岁,显著低于无病毒感染组平均发病年龄19.69±8.98岁(P<002)。所有病例中大约四分之一的病人有糖尿病家族史,明显高于国外类似报道。 A retrospective study of 139 cases of IDDM patients(male 54 cases,female 85 cases)were investi-gated. Average age 31.74 ±12.20 yr.One third of all patients had virus infection before the onset of IDDM and the infection in upper respiratory system and intestine occupied most of the cases(85%).In two cases, the onset of the disease was induced after BCG vaccination. There is no relationship between virus infection and the occurance of DKA as primary form of onset. The average age in the group of positive virus infection is significantly younger than in the group of negative virus infection (P< 0.02).About one fourth of all cases had positive family history of diabetes which is much higher than the simi-lar reports in Westen countries.
出处 《中华内科杂志》 CAS CSCD 北大核心 1994年第1期37-39,共3页 Chinese Journal of Internal Medicine
关键词 糖尿病 胰岛素 依赖型 感染 Diabetes mellitus. insulin-dependent Infection
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  • 1周仁,国外医学内分泌学分册,1990年,4卷,169页 被引量:1

同被引文献5

  • 1程桦,张莹,傅祖植,严棠.胰岛素依赖型糖尿病起病年龄相关的HLA-DQA1遗传异质性[J].中山医科大学学报,1996,17(3):205-209. 被引量:4
  • 2张胜兰 唐天华 等.胰岛素依赖型糖尿病与病毒抗体[J].中华医学杂志,1992,(72):174-174. 被引量:2
  • 3[3]Banatvala JE Bryant J, Schern thamer G (1985). Coxsackie B.Mumps rubella and cytomegalovirus specific IgM responses in patients with junvenile onset insulindependent diabetes mellitus in britain austria and australia. Lancet, 1992, 1:1409 被引量:1
  • 4杨晓,中华内科杂志,1994年,33卷,1期,37页 被引量:1
  • 5张胜兰,中华医学杂志,1992年,72卷,3期,174页 被引量:1

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