摘要
目的 寻找对结核性腹水高敏感、高特异而又简单的检查方法。方法 采用改良的Martineck法和ELISA法对 4 5例结核性腹水腺苷脱氨酶 (ADA)和结核抗体水平进行了检测 ,并以 4 2例恶性腹水和 2 8例肝硬化腹水作对照。结果 结核性腹水ADA和结核抗体水平显著高于对照组 (P <0 .0 1)。以ADA >30U/L作为阳性标准 ,其对结核性腹水的敏感性为 10 0 % ,特异性为 98.6 % ,准确性为 99.2 % ;结核抗体对结核性腹水的敏感性为 90 % ,特异性为 93.3% ,准确性为 92 %。结论 ADA和结核抗体对诊断结核性腹水均有重要价值。在使用抗结核药特别是在并用激素治疗后 ,腹水ADA及结核抗体水平会随之下降 ,故应在停药 1周后检测并动态观察二者的变化。
Objective To seek diagnostic tests with high sensitivity,specificity and simplicity for tuberculous ascites. Methods Adenosine deaminase (ADA) and anti-TB in ascites were tested by modified Martineck's method and ELISA in 45 cases of tuberculous ascites, 42 cases of carcinous ascites and 28 cases of cirrhotic ascites were tested as the control group. Results The level of ADA and anti-TB in ascites was remarkably higher in tuberculous ascites than that in carcinous ascites and cirrhotic ascites (P<0.01). When ADA was above 30U/L and positive anti-TB were present, their sensitivity, specificity and accuracy in diagnosis of tuberculous ascites were 100%, 98.6%, 99.2% and 90%, 93.3%, 92% respectively. Conclusion The tests of ADA and anti-TB in ascites are very important in diagnosis of tuberculous ascites.
出处
《菏泽医学专科学校学报》
2000年第2期79-81,共3页
Journal of Heze Medical College
关键词
腺苷脱氨酶
结核抗体
结核性腹水
Adenosine deaminase(ADA)
Anti-TB
tberculous ascites
