摘要
目的:观察急性心肌梗死(AMl)后血清中心肌肌钙蛋白Ⅰ(cTnI)的动态变化。方法:应用ELlSA法,使用∑960酶标仪连续测定19例AMI早期(l～8小时)入院患者和118例正常人血清中cTnI,结果与心肌酶(CK-MB)对比。结果:AMl时血清中cTnI升高时间较早,持续时间更长,对心肌细胞损伤诊断的准确性、灵敏性和特异性均优于心肌酶。
Objective:To observe the dynamic changes of serum myocardial troponin I(cTnI) in patients with acute myocardial infarction(AMI).Methods:Blood samples were respectively obtained at admission 6,12,48 hours and 10 days later from 19 patients with acute myocardial infarction and those in 118 normal subjects served as controll group.With ELISA method,the serum concentrations cTnI in the two groups were simulataneously measured by ∑960 apparatus and compared with CK-MB.Results:The rising time of serum cTnI in AMI was earlier and its duration was longer.It was superior to CK-MB in veracity,sensitivity and specificity for diagnosic of myocardial damage.Conclusion:The present study suggests that quantitative determination of serum cTnI has very important clinical value on diagnosis of acute myocardial infarction.
出处
《现代医药卫生》
2003年第9期1095-1096,共2页
Journal of Modern Medicine & Health
