摘要
一次经口给大白鼠硝基苯造成肝细胞的脂质过氧化。脂质过氧化物(LPO)的含量在给药后(200mg/kg体重的硝基苯)3小时达最高峰,并具有剂量。效应关系,二者呈正相关。硝基苯还促使鼠肝细胞的CytP-450和SOD含量下降。
itrobenzene(NB)could induce lipid perOxidation in liver cells of rats after a single
dose of 200mg/kg was admin-istrated.Lipid peroxide(LPO)level reached the maximum at 3 hours
after NB treatment. There was positive dose-effectrelationship.NB could also reduce the content of
Cyt P-450 and SOD in rat liver cells significantly;
出处
《中华劳动卫生职业病杂志》
CAS
CSCD
1994年第3期27-28,共2页
Chinese Journal of Industrial Hygiene and Occupational Diseases