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罗-利与布-利混合液硬膜外麻醉在子宫切除术中的临床应用

Clinical Comparison of Epidural Anesthesia with Ropivacaine Lidocaine and Bupivacaine
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摘要 目的 比较0 .2 5 %罗哌卡因- 1 5 %利多卡因混合液与0 . 1875 %布比卡因- 1 5 %利多卡因混合液硬膜外麻醉在子宫切除手术中的临床应用效果。方法 ASAⅠ-Ⅱ级择期拟行子宫切除术病人4 0例,随机分为两组Ro组与Bu组,每组2 0例。Ro组硬膜外给予0 . 2 5 %罗哌卡因- 1 5 %利多卡因混合液,再加入1:2 0万u的肾上腺素。Bu组硬膜外给予0 .1875 %布比卡因- 1 5 %利多卡因混合液,再加入1:2 0万u的肾上腺素。比较两组病人在感觉、运动神经阻滞方面的异同,并观察用药后的血液动力学变化和不良反应。结果 两组病人感觉神经阻滞起效时间、最高止痛平面无差异(P >0 . 0 5 ) ,T10止痛平面维持时间Ro组非常明显短于Bu组(P <0 . 0 1)。下肢运动神经阻滞起效时间(Bromage评分1分)和完全阻滞时间(Bromage评分3分)Ro组慢于Bu组(P <0 . 0 1)。下肢运动神经阻滞持续时间Ro组短于Bu组(P <0 . 0 5 )。结论 硬膜外给予0 . 2 5 %罗哌卡因-1 5 %利多卡因混合液用于子宫切除手术是安全有效的。 Objective To evaluate the efficacy and safety of 0.25% ropivacaine-1.5%lidocaine in patients undergoing hysterectomy. Methods Forty patients ASA class Ⅰ-Ⅱ undergoing elective hysterectomy, were randomly allocated to receive 0.25% ropivacaine-1.5%lidocaine (Ro group n=20),0.1875% bupivacaine-1.5%lidocaine combined with epinephrine respectively for epidural anesthesia. Results There was no significant difference between the two groups in the onset time and the peak level of sensory block level(P>0.05).As compared with Bu group, the duration time of sensory block on T10 was shorter significantly (P<0.01), the onset of motor block ( Bromage scale was 1), the time to peak motor block ( Bromage scale was 3) was prolonged significantly (P<0.01),the duration time of motor block was shorter(P<0.05). Conclusions 0.25% ropivacaine-1.5%lidocaine is safe and effective for epidural anesthesia in patients undergoing hysterectomy.
出处 《锦州医学院学报》 2005年第2期40-42,共3页 Journal of Jinzhou Medical College
关键词 罗哌卡因 布比卡因 硬膜外麻醉 ropivacaine bupivacaine epidural anesthesia
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参考文献4

  • 1Arakawa M, Aoyama Y, Ohe Y.Efficacy of 1% ropivacaine at sacral segments in lumbar epidural anesthesia [J]. Reg Anesth Pain Med, 2003, 28 (3): 208-214. 被引量:1
  • 2李秀泽,谭玲.罗哌卡因的研究近况及临床应用[J].实用医药杂志,2004,21(6):554-555. 被引量:10
  • 3Higuchi H, Adachi Y, Kazama T.Factors affecting the spread and duration of epidural anesthesia with ropivacaine [J]. Anesthesiology, 2004, 101 (2): 451-460. 被引量:1
  • 4Camorcia M, Capogna G, Lyons G, et al.The relative motor blocking potencies of intrathecal ropivacaine: effects of concentration [J]. Anesth Analg, 2004, 98 (6): 1779-1782. 被引量:1

二级参考文献25

  • 1吕安祺,王珊娟,杭燕南,林建华.罗比卡因硬膜外腔阻滞在分娩镇痛中的应用[J].临床麻醉学杂志,2001,17(5):243-245. 被引量:11
  • 2[1]Mcclellan KG, Faulds D. Ropivacaine, an update of its use in regional anaesthesia. Drugs,2000,60(5):1065 被引量:1
  • 3[2]Ohmura S, Kawada M,Ohta T,et al. Levobupivacaine,or ropivacaineinfused rat. Anesth Analg,2001,93(3):743 被引量:1
  • 4[3]Groban L, Deal DD, Vernon JC, et al. Cardial resuscitation after incremental overdosage with lidocaine, bupivacaine,levobupivacaine,and ropivacaine in anesthetized dog. Anesth Analg,2001,92(1):37 被引量:1
  • 5[4]Knudsenk,Beckmans,Sunkula M.Central nervous and cardiovascular effect of iv infusions of ropivacaine, bupivacaine and placebo in volunteers. Br J Anesth, 1997,78(1):507 被引量:1
  • 6[5]Liu BG, Zhuang XL, Li ST, et al. Effects of bupivacaine and ropivacaine on high-voltage-activated calcium currents of the dorsal horn neurons in newborn rats. Anesthesiology, 2001,95(1):139 被引量:1
  • 7[6]Graf BM.The cardiotoxicity of local anesthetics: the place of ropivacaine. Curr Top Med Chem,2001,1(3):207 被引量:1
  • 8[9]Neustein S, Sampson I, Dimich I, et al. Milrinone is superior to epinephrine as treatment of myocardial depression due to ropivacaine in pig. Can J Anesth,2000,47(11):1114 被引量:1
  • 9[10]Casati A, Santorsola R, Cerchierini E,et al. Ropivacaine. Minerva Anesthesiol,2001,67(suppl 1):15 被引量:1
  • 10[11]Oda A, Ohash H, Komori S,et al. Characteristics of ropivacaine block of Na+ channels in rat dorsal root ganglion neurons. Anesth Analg,2000,91 (5): 1213 被引量:1

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