摘要
目的 比较0 .2 5 %罗哌卡因- 1 5 %利多卡因混合液与0 . 1875 %布比卡因- 1 5 %利多卡因混合液硬膜外麻醉在子宫切除手术中的临床应用效果。方法 ASAⅠ-Ⅱ级择期拟行子宫切除术病人4 0例,随机分为两组Ro组与Bu组,每组2 0例。Ro组硬膜外给予0 . 2 5 %罗哌卡因- 1 5 %利多卡因混合液,再加入1:2 0万u的肾上腺素。Bu组硬膜外给予0 .1875 %布比卡因- 1 5 %利多卡因混合液,再加入1:2 0万u的肾上腺素。比较两组病人在感觉、运动神经阻滞方面的异同,并观察用药后的血液动力学变化和不良反应。结果 两组病人感觉神经阻滞起效时间、最高止痛平面无差异(P >0 . 0 5 ) ,T10止痛平面维持时间Ro组非常明显短于Bu组(P <0 . 0 1)。下肢运动神经阻滞起效时间(Bromage评分1分)和完全阻滞时间(Bromage评分3分)Ro组慢于Bu组(P <0 . 0 1)。下肢运动神经阻滞持续时间Ro组短于Bu组(P <0 . 0 5 )。结论 硬膜外给予0 . 2 5 %罗哌卡因-1 5 %利多卡因混合液用于子宫切除手术是安全有效的。
Objective To evaluate the efficacy and safety of 0.25% ropivacaine-1.5%lidocaine in patients undergoing hysterectomy. Methods Forty patients ASA class Ⅰ-Ⅱ undergoing elective hysterectomy, were randomly allocated to receive 0.25% ropivacaine-1.5%lidocaine (Ro group n=20),0.1875% bupivacaine-1.5%lidocaine combined with epinephrine respectively for epidural anesthesia. Results There was no significant difference between the two groups in the onset time and the peak level of sensory block level(P>0.05).As compared with Bu group, the duration time of sensory block on T10 was shorter significantly (P<0.01), the onset of motor block ( Bromage scale was 1), the time to peak motor block ( Bromage scale was 3) was prolonged significantly (P<0.01),the duration time of motor block was shorter(P<0.05). Conclusions 0.25% ropivacaine-1.5%lidocaine is safe and effective for epidural anesthesia in patients undergoing hysterectomy.
出处
《锦州医学院学报》
2005年第2期40-42,共3页
Journal of Jinzhou Medical College