摘要
对７０例卵巢良、恶性肿瘤，３１例妇科其他恶性肿瘤患者和３５例对照者的血清，进行乳酸脱氢酸（ＬＤＨ）及其同工酶、唾液酸（ＳＡ）、癌胚抗原（ＣＥＡ）、β＿２－微球蛋白（β＿２－ＭＧ）和碱性磷酸酶（ＡＫＰ）六项指标检测。结果：（１）卵巢恶性肿瘤患者血清中六项指标均值高于对照者和卵巢良性肿瘤患者；与妇科其他恶性肿瘤患者比较，除ＬＤＨ及ＬＤＨ同工酶以外，其余无显著性差异。（２）Ⅲ、Ⅳ期卵巢癌患者的六项指标阳性率高于Ⅰ、Ⅱ期患者；上皮性癌患者的ＬＤＨ、ＬＤＨ同工酶、ＣＥＡ及β＿２－ＭＧ的阳性率高于非上皮性癌。（３）判断卵巢肿瘤的良、恶性，单项指标以ＬＤＨ同工酶的诊断性能为最好，其次依次为ＬＤＨ、ＳＡ、ＣＥＡ、β＿２－ＭＧ和ＡＫＰ；多项指标组合以ＬＤＨ＋ＬＤＨ同工酶＋ＳＡ的诊断性能为最好。
hirty-five cases of ovarian cancer, 35 ovarianbenign tumors, 31 other gynecologic cancer and 35normal controls were assayed for LDH,LDHisonezyme, SA, CEA, β_2-MG and AKP. Theresults showed:(1)The average content of tumormarkers in ovarian cancer was higher than benign tu-mor and healthy controls. (2)The positive rate of tu-mor markers in stage Ⅰ and Ⅱ patients of ovarian can-cer was lower than in stage Ⅲ and Ⅳ. (3) In the tumormarkers, the diagnostic value of LDH-isonezyme forovarian cancer was best. (4)Combined assaying LDH,LDH-isonezyme and SA was superior to using onemarker for the diagnosis of ovarian cancer.
出处
《中华妇产科杂志》
CAS
CSCD
北大核心
1994年第6期336-339,共4页
Chinese Journal of Obstetrics and Gynecology
关键词
卵巢肿瘤
乳酸脱氢酶
唾液酸
抗原
Ovarian neoplasma Lactatedehydrogenase isoenzyme Sialic acidsCarcinoembryonic antigen Diagnosis
