摘要
在食管癌、胃癌高发区农村,对35岁以上男女476人,采用同步盲法依次应用肿瘤耳部信息诊断仪、隐血珠、拉网细胞学、胃镜、刷片、组织学活检6种方法进行了筛查诊断,并应用判定矩阵统计学方法对其敏感性、特异性、符合率、正确指数、阳性预报值、阴性预报值等14项指标进行了综合评价.结果表明食管拉网细胞学检查是普查发现食管癌、贲门癌的较好方法.应用纤维胃镜直视、刷片或活检对于明确诊断有重要作用,但也有一定局限性.对每项检查的费用和效益进行了综合分析,并对普查和临床应用提出了建议.
In the rural areas with high-incidence of esophageal and gastric cancer,mass screeninghas been done in 476 male and female .subjects, aged over 35 by using in turn 6 approaches-ear information diagnostic instrument,occult blood tesf,balloon cytologic examination, endoscopy, smear and biopsy,and 14 indices including sensitivity,specificity,predictable positive and negative values,correct indices,rate of agreement,etc. were evaluated comprehensively with the statistical method of decision matrix. The results showed that the balloon cytologic examination was a good method for the esophageal and cardiac cancer detection. Although important roles could be played by direct vision under endoscopy and smear and biopsy,these modalities had their limitations. The expenses and benefits of thes'e examinations together with suggestions for general screening and clinical application were also put forward.
出处
《中国肿瘤临床》
CAS
CSCD
北大核心
1994年第6期408-411,共4页
Chinese Journal of Clinical Oncology
关键词
癌
筛查
诊断
食管肿瘤
胃肿瘤
Early detection Esophagus Stomach Cancer Cost-benefit
