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甘利欣注射液治疗酒精性肝病临床研究 被引量:1

Clinical study in treating alcoholic liver disease with diammonium glycyrrhizinate
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摘要 目的研究甘利欣注射液治疗酒精性肝病临床疗效。方法选择酒精性肝病住院病人200例,随机分为治疗组120例,给予甘利欣注射液治疗;对照组80例,给予门冬氨酸钾镁+肌苷静脉滴注。结果治疗组总有效率98.0%,对照组总有效率64.1%,2组相比差异显著(P<0.01),治疗组显效所需时间为(9.7±3.2)d,明显少于对照组(P<0.01)。1个疗程结束,治疗组ALT、AST、GGT、TG、CHO下降幅度均明显高于对照组(P均<0.01),治疗组ALT、AST、GGT、TG、CHO复常率分别为97.6%、95.5%、89.5%、87.6%、78.5%,与对照组相比也有明显差异(P均<0.01)。结论甘利欣注射液治疗酒精性肝病疗效明显。 Objective To study clinical therapeutic effects on treating alcoholic liver disease with diammonium glycyrrhizinate. Methods 200 patients with alcoholic liver disease were randomly divided into therapeutic group(120 cases) and control group(80 cases). The therapeutic group was treated with diammonium glycyrrhizinate. The control group was treated with potassium magnesium aspartate and inosine. Results The effective rate in the therapeutic group and the control group were 98.0% and 64.1%(P<0.01). The time of presenting significant effect in the therapeutic group meanly was(9.7±3.2)days, much less than the control group needed(P<(0.01)). At the end of therapeutic course the ALT, AST, GGT, TG, CHO decreasing rates in the therapeutic group were higher than in the control group(P<0.01, respectively). The ALT, AST, GGT, TG, CHO normal rates in the therapeutic group were 97.6%, 95.5%, 89.5%, 97.6%, 78.5%, respectively, it was better than in the control group(P<0.01, respectively). Conclusion Treating alcoholic liver disease with diammonium glycyrrhizinate had significant effect, it was better than with potassium magnesium aspartate.
出处 《中国厂矿医学》 2005年第3期205-207,共3页 Chinese Medicine of Factory and Mine
关键词 甘利欣 酒精性肝病 门冬氨酸钾镁 肌苷 治疗 Alcoholic liver disease Diammonium glycyrrhizinate Potassium magnesium aspartate Inosine
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